Prosthetic Heart Valves, Part I: Identification and Potential Complications

Jagdish Butany, MBBS, MS, FRCPC; Gursharan S. Soor, BSc; Moyukh Chakrabarti, BSc; Iva Vukin, BSc; Shaun W. Leong, BSc


Geriatrics and Aging. 2006;9(10):691-696. 

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Medtronic Freestyle® (Medtronic)

This valve has excellent hemodynamics and is, in fact, a biological valved conduit that is used for aortic root replacement. Recent studies on long-term explants show a cellular reaction to the aortic tissues, suggesting a low-grade cellular rejection-like phenomenon.

An eight-year study reports 100% freedom from structural valve deterioration and an overall survival rate of 83%.[34] Matsue et al.[35] reported that a small group of patients who had 21 mm valves implanted using the subcoronary technique expressed a suboptimal flow pattern, and therefore recommend extra attention when dealing with such a situation. A recent study by Butany et al.[36] on a series of explanted Freestyle® bioprostheses reports that inflammatory cells appear to play a significant role in prosthesis failure.


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