Rapid Atrophy of the Lumbar Multifidus Follows Experimental Disc or Nerve Root Injury

Paul Hodges, PhD*; Allison Kaigle Holm, PhD†; Tommy Hansson, PhD†; Sten Holm, PhD†

Disclosures

Spine. 2006;31(25):2926-2933. 

In This Article

Conclusion

This study provides evidence that rapid changes in the lumbar multifidus occur after injury to a lumbar intervertebral disc, which may be due to disuse following reflex inhibitory mechanisms. These data confirm the possibility for rapid atrophy to occur in LBP at a single segment. Reduced water content and lactate concentration were found, along with histologic changes, but cannot explain the acute cross-sectional area changes. However, they may contribute to chronic changes in the multifidus.

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