Rapid Atrophy of the Lumbar Multifidus Follows Experimental Disc or Nerve Root Injury

Paul Hodges, PhD*; Allison Kaigle Holm, PhD†; Tommy Hansson, PhD†; Sten Holm, PhD†


Spine. 2006;31(25):2926-2933. 

In This Article


This study provides evidence that rapid changes in the lumbar multifidus occur after injury to a lumbar intervertebral disc, which may be due to disuse following reflex inhibitory mechanisms. These data confirm the possibility for rapid atrophy to occur in LBP at a single segment. Reduced water content and lactate concentration were found, along with histologic changes, but cannot explain the acute cross-sectional area changes. However, they may contribute to chronic changes in the multifidus.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as: