Trying to Keep Ahead of Lice: A Therapeutic Challenge

C. E. Malcolm, MD, CCFP; J. N. Bergman MD, FRCPC


Skin Therapy Letter. 2006;11(10):1-6. 

In This Article


Permethrin 1% (Nix®) is a poorly absorbed synthetic pyrethrin with pediculicidal and ovicidal activity. It blocks sodium channel repolarization of the louse neuron resulting in respiratory paralysis and death. By leaving a residue on the hair, it remains active for 2 weeks following application.[5] After washing hair, rinsing with water, and towel drying, it is applied to the scalp and hair for 10 minutes and then rinsed out. To ensure a cure, many practitioners recommend a second treatment approximately 1 week later as any eggs not killed by first treatment will be hatching.


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