Trying to Keep Ahead of Lice: A Therapeutic Challenge

C. E. Malcolm, MD, CCFP; J. N. Bergman MD, FRCPC


Skin Therapy Letter. 2006;11(10):1-6. 

In This Article


Lindane (gamma benzene hexachloride) 1% lotion is pediculicidal but it has limited ovicidal activity. This organochloride kills lice by causing CNS stimulation and respiratory paralysis. Given lindane´s increased side-effect potential including neurotoxicity and bone marrow suppression, it is considered a second-line treatment.[5] Lindane remains on the market as an alternative when other treatments have failed. It is contraindicated in children under 2 years, pregnant women, and nursing mothers.


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