COMMENTARY

Possible Role of Moringa oleifera Lam. Root in Epithelial Ovarian Cancer

Chinmoy K. Bose, MD, PhD

Disclosures

February 06, 2007

Conclusion

A hormonal etiology of epithelial ovarian cancer has long been suspected, and now the role of FSHR has also been demonstrated.[26] Moringa oleifera can interfere with hormone receptor-related and neoplastic growth-related cytokine pathways via centrally acting mechanisms. It appears to have a tremendous effect on G protein-linked signal transduction system as well. Thus, the effects of Moringa oleifera Lam. in the treatment of epithelial ovarian cancer are worth investigating. The first stage of an experiment using Swiss-strain adult female mice is being completed by the present author to determine the effects of Moringa oleifera Lam. root, and results to date have proven to be similar to those demonstrated by Shukla and colleagues.[15] Further studies will be conducted at the receptor level, in ovarian cancer cell lines, and in experimental (ie, induced) ovarian cancer.

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