Topical Treatments for Melasma and Postinflammatory Hyperpigmentation

C.B. Lynde; J.N. Kraft, MD; C.W. Lynde, MD, FRCPC


Skin Therapy Letter. 2006;11(9):1-6. 

In This Article

Hyperpigmentation Treatments

Therapeutic goals for hyperpigmentation include promoting the degradation of melanosomes, inhibiting the formation of melanosomes, and retarding the proliferation of melanocytes.[11] Because sun exposure is an important etiologic factor in hyperpigmentation, all patients should use daily, broad-spectrum, high SPF sunscreens and minimize sun exposure.[12] Although this practice is widely used there are no clinical trials to support its therapeutic benefit. Most of the therapies used for hyperpigmentation have been studied in melasma and the same treatment principles hold for PIH.[3]


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