COMMENTARY

The Genetics of Attention-Deficit/Hyperactivity Disorder: Current Status and Clinical Implications

Stephen V. Faraone, PhD

November 02, 2006

Introduction

The past 3 decades have taught us much about the etiology of attention-deficit/hyperactivity disorder (ADHD). Of greatest importance, we know that multiple genetic and environmental risk factors work together to cause this disorder and no single risk factor stands out as a necessary and sufficient cause. In this review, we examine evidence showing that ADHD is strongly influenced by genes, describe genes that increase susceptibility to ADHD or modulate treatment response, and discuss the clinical implications of these findings.

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