Eccrine hidrocystomas and apocrine hidrocystomas have a very similar presentation, and their distinction from other head and neck cyst-like lesions must ultimately be verified on biopsy and by careful examination under the microscope. For both types, cystic lesions such as epidermal inclusion cysts, mucoid cysts, hemangioma, and lymphangioma are considered in the differential. Attention is given to cysts (mostly apocrine hidrocystomas) that resemble basal cell carcinoma of the eyelid or malignant melanoma because of their color (typically blue-black). A biopsy of the lesions is very important to exclude these diagnoses.
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Cite this: Hidrocystomas - A Brief Review - Medscape - Sep 05, 2006.