Treatment Options for the Eradication of Intestinal Protozoa

Michael JG Farthing

Disclosures

Nat Clin Pract Gastroenterol Hepatol. 2006;3(8) 

In This Article

Encephalitozoon SPP.

Unlike E. bieneusi, other Microsporidium Encephalitozoon spp. are widespread amongst humans and other mammals. Infection with Encephalitozoon intestinalis (formerly known as Septata intestinalis) has been reported in patients with AIDS in developed countries and in Africa.[63] This organism is invasive, and develops within a parasitophorous vacuole that is septated; this feature allows infection with E. intestinalis to be distinguished from that caused by E. bieneusi.

The parasite is more sensitive to albendazole than are the other microsporidia, and albendazole 400 mg twice daily for 4 weeks can relieve symptoms of diarrhea and eradicate the parasite from HIV-infected patients.[60]

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