Therapy Insight: Clinical Management of Pregnant Women With Epilepsy

Alison M. Pack


Nat Clin Pract Neurol. 2006;2(4):190-200. 

In This Article


Pregnancy is associated with dynamic changes in the body, and for women with epilepsy who are undergoing treatment with antiepileptic drugs (AEDs) there are unique management concerns. This review highlights how seizure frequency can change during pregnancy, and the potential effects of epilepsy and AEDs on the developing fetus, illustrated by results from both retrospective and prospective studies. This article also discusses specific management issues for women with epilepsy during pregnancy, including preconceptual counseling, monitoring of AED levels and vitamin K prophylaxis, and recommendations with regard to breastfeeding.


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