Ovarian Hormones and Migraine Headache: Understanding Mechanisms and Pathogenesis--Part 2

Vincent T. Martin, MD; Michael Behbehani, PhD


Headache. 2006;46(3):365-386. 

In This Article

Menstrual Cycle

Migraine headaches could theoretically be influenced by changes in ovarian hormones that occur throughout the female menstrual cycle. Knowledge of the different "hormonal milieus" encountered during different phases of the menstrual cycle is essential to an understanding of the effects of ovarian hormones on migraine headache. Therefore, in the next several sections, we will review the endocrinology of the menstrual cycle as well as the potential mechanisms through which ovarian hormones could modulate menstrual and nonmenstrual migraine headaches.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.