Staphylococcus Aureus Pneumonia: Emergence of MRSA in the Community

Suzanne F. Bradley, MD


Semin Respir Crit Care Med. 2005;26(6):643-649. 

In This Article

General Guidelines for Treatment of CA-MRSA Pneumonia

Given its high morbidity and mortality, the treatment of staphylococcal pneumonia has primarily relied on intravenous therapy with a bactericidal antibiotic. Experts have recommended 10 to 14 days of therapy in patients with rapid resolution of symptoms and chest roentgenographic findings.[16,25] Duration of therapy should be based on careful follow-up for resolution of signs and symptoms of infection in patients with primary pulmonary infection with cavitary disease or empyema. All bacteremic patients should be carefully assessed for the presence of endocarditis, empyema, metastatic abscesses, and other complications that might require longer therapy and surgical intervention. For S. aureus, clinical examination and duration of bacteremia are not useful to exclude the diagnosis of endocardtis.[45] Prolonged intravenous therapy is required unless the patient has well-documented and uncomplicated isolated right-sided endocarditis.


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