Aldosterone Antagonists in the Treatment of Heart Failure

Todd R. Marcy; Toni L. Ripley


Am J Health Syst Pharm. 2006;63(1):49-58. 

In This Article


Spironolactone and eplerenone are life-saving agents for patients with advanced heart failure and may benefit patients with mild heart failure. Patients' potassium levels and renal function must be routinely assessed to minimize the risk of life-threatening hyperkalemia.