The Clinical Presentation of Ehlers-Danlos Syndrome

Elizabeth J. Lawrence, RNC, MSN, NNP


Adv Neonatal Care. 2005;5(6):301-314. 

In This Article


Ehlers-Danlos syndrome can present in the newborn period. The 6 major types of EDS explain the wide variation in presentation and clinical findings. Early genetic counseling will help couples make the appropriate reproductive decisions. If an infant presents with suspicious clinical findings, classification of his or her symptoms based on the major and minor diagnostic criteria should be attempted. If the family history is positive, the EDS type will be useful in further focusing the evaluation. Whenever possible, laboratory confirmation of the diagnosis is recommended. Understanding each type of EDS and the type-specific problems will help the multidisciplinary healthcare team meet the infant's needs and provide anticipatory guidance and support for the family. The ultimate goal is to preserve and optimize quality of life for the individual with EDS.


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