Stress and Resilience: Implications for Depression and Anxiety

Jerrold F. Rosenbaum, MD; Jennifer M. Covino, MPA


December 29, 2005

In This Article


The biological reaction to stressful events is multifaceted, involving several neurochemical systems that work together in a complex and interactive manner. Greater understanding of the biological systems involved in reactions to stress and the biological mechanisms by which the organism may protect itself from trauma is well under way. This research is confounded, however, by the complex interaction of environmental and genetic factors. Nonetheless, new neuroscience tools have opened a window that has begun to provide investigators the opportunity to examine these biological systems and explore protective factors that may, in turn, lead to pharmacologic and/or psychosocial treatments that influence resilience and recovery.


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