Substance Abuse and Bipolar Disorder

Marcia L. Verduin, MD; Bryan K. Tolliver, MD, PhD; Kathleen T. Brady, MD, PhD


December 05, 2005

In This Article


Bipolar disorder and SUDs frequently co-occur, and these disorders have a negative impact on each other. While a limited number of studies have addressed treatment of these disorders, there is a significant need for further clinical research, particularly double-blind trials, focused on treatment of co-occurring bipolar disorder and SUDs. Further, there is need for investigation of pharmacologic agents used to treat SUDs, such as naltrexone and acamprosate, in individuals with bipolar disorder.


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