Classification and Treatment of Urticaria: A Brief Review

Kjetil Kristoffer Guldbakke, MD; Amor Khachemoune, MD, CWS


Dermatology Nursing. 2005;17(5):361-364. 

In This Article

Contact Urticaria

Contact urticaria develops at the site(s) of contact of an urticant, and the diagnosis is usually self-evident. It can be divided into an allergic subgroup caused by an IgE-allergen interaction and a non-allergic subgroup, which is IgE independent. The allergic form is typically seen in children with atopic dermatitis sensitized to environmental allergens such as grass, animals, food, or latex, and may be complicated by anaphylaxis. This type appears within minutes, fades within 2 hours, and is partially inhibited by antihistamines. The non-allergic contact urticaria is due to the direct effect of the urticant on blood vessels, and includes irritants as benzoic acid and cinnamic aldehyde in cosmetics. It may take 45 minutes for lesions to appear, and is inhibited by nonsteroidal anti-inflammatory drugs (NSAIDs).


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