Classification and Treatment of Urticaria: A Brief Review

Kjetil Kristoffer Guldbakke, MD; Amor Khachemoune, MD, CWS


Dermatology Nursing. 2005;17(5):361-364. 

In This Article

Urticarial Vasculitis

Urticarial vasculitis represents 5% to 10% of cases of chronic urticaria, characterized histologically by the presence of vasculitis on skin biopsy. Clinically it tends to last longer than "ordinary" urticaria and be more painful and itchy. Lesions often occur at pressure points, and may resolve with residual purpura. Extra-cutaneous manifestations include transient and migratory arthralgias (50%), gastrointestinal symptoms (20%), and pulmonary obstructive disease (20%), particularly in smokers. Renal disease with proteinuria or hematuria occurs in 5% to 10% of patients, but progression to severe renal disease is uncommon. The clinical course is usually benign, on average lasting 3 years. Urticarial vasculitis may be associated with systemic lupus erythematosus, Sjögren's syndrome, hypocomplementemia, or cryoglobulinemia.


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