Nosocomial Infections Due to Multidrug-Resistant Pseudomonas Aeruginosa: Epidemiology and Treatment Options

Marilee D. Obritsch, PharmD; Douglas N. Fish, PharmD, FCCM; Robert MacLaren, PharmD; Rose Jung, PharmD

Disclosures

Pharmacotherapy. 2005;25(10):1353-1364. 

In This Article

Infection Control

A rapid rise in MDRPA infections in non-outbreak settings is a threat that clinicians worldwide will be fighting in the years to come. However, outbreak situations with MDRPA strains within institutions remain a concern. Clonal dissemination has been linked to negligent hygiene issues and contaminated tap water[7] or equipment.[61] An improvement in infection control measures, including hand hygiene, revised equipment procedures, and isolation precautions, have been used to eliminate outbreaks.

Surveillance of institution-specific resistance patterns is a crucial component of early detection of strains and may have a substantial impact on nosocomial infection rates.[62] Another consideration is the variation in susceptibilities between units within individual institutions, as differences have been reported when comparing whole hospital antibiogram data with intensive care unit-specific antibiogram data.[63] Surveillance of this nature allows problems within units to be identified more quickly than waiting for a change in hospitalwide susceptibility data. As MDRPA infection rates rise, active infection control teams and surveillance programs will play a crucial role in early detection, treatment, and, we hope, containment of such infections.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....