Effects of Herbal Supplements on the Kidney

Wendell Combest; Marian Newton; Austin Combest; June Hannay Kosier

Disclosures

Urol Nurs. 2005;25(5):381-386. 

In This Article

Herbs and the Transplant Patient

The transplant patient is also at risk for complications from herbal remedies such as Echinacea (Echinacea purpurea), which is promoted as an immune system stimulant (Combest & Nemecz, 1997). This effect could endanger the transplant patient taking immunosuppressant drugs. Furthermore, St. John's wort (Hypericum perforatum) causes a decrease in cyclosporine, an immunosuppressant, serum levels thus compromising the success of the organ transplant (Mandelbaum, Pertzborn, Martin-Facklam, & Wiesel, 2000). Although not yet demonstrated, many other herbal supplements may have a similar effect on the metabolism of cyclosporine as well as other drugs used to treat the transplant patient (see Table 1 ).

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