Medication Adherence: A Literature Review

Charlotte A. Kenreigh, PharmD, and Linda Timm Wagner, PharmD


October 12, 2005

In This Article

Adolescent Transplant Recipients

Adolescence is a difficult transition period for healthy individuals, and it brings even greater challenges for patients with chronic diseases. In the transplant population, long-term outcomes (> 5 years post-transplantation) are significantly worse for this age group than for younger pediatric patients.[1]

A recent paper reviewed the published information on the prevalence, determinants, and consequences of nonadherence with immunosuppressive treatment in the adolescent transplant patient.[1] Although data on the effectiveness of interventions geared at improving adherence in this population are limited, pharmacists clearly must take a proactive role in helping these patients recognize the importance of taking their medications. This may include providing the adolescent with additional education, both verbal and nonverbal, simplifying the regimen whenever possible, identifying possible reward systems for good adherence, providing information on the cosmetic side effects of their treatment and how to manage them, and involving the family in these strategies.


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