W. Steven Pray, PhD, DPh

Disclosures

US Pharmacist. 2005;30(7) 

In This Article

Treatment

Meniere's cannot be cured. However, the pharmacist can help with useful tips and can explain the use of prescribed medications.

During an attack, the patient will need help in walking to a safe place to sit or lie down. Hearing aids may be necessary for any hearing loss that persists. Patients must be exhorted to rest quietly during attacks, rather than attempt to carry out normal activities of daily living. Reading, bright lights, video game playing, and television watching may worsen an ongoing episode.

One method of treatment is aimed at reducing pressure in the endolymphatic sac. Triamterene/hydrochlorothiazide may be taken between attacks to reduce the fluid accumulation.[5] During an acute attack, meclizine 12.5 mg once daily up to 50 mg three times daily may be helpful. Physicians have also prescribed lorazepam, promethazine (oral or rectal), and dexamethasone.

When oral medications fail, physicians may attempt to solve debilitating Meniere's disease in a more direct manner. Surgery on the endolymphatic sac can provide relief while maintaining inner ear function.[3] In another approach, gentamicin is instilled into the middle ear to take advantage of the well-known ototoxicity of aminoglycosides. However, the risk of vestibular and cochlear toxicity must be weighed against the possible relief to be obtained from the procedure.[3]

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