Contact Allergen of the Year: Corticosteroids

Marléne Isaksson; Magnus Bruze


Dermatitis. 2005;16(1):3-5. 

In This Article


Corticosteroids still constitute the main armamentarium for the symptomatic treatment of inflammatory skin diseases. One drawback that has been recognized during the last 10 to 15 years is hypersensitivity to these substances; delayed-type hypersensitivity is by far the most common, but type I allergy has also been observed. Routine patch testing with one or two corticosteroids in consecutively tested dermatitis patients has detected a fairly high frequency of hypersensitivity to corticosteroids after topical as well as systemic administration; figures of up to 5% have been presented.[1,2,3,4,5] The three aspects of corticosteroid contact allergy that we wish to focus on here must be considered; otherwise, the risk of missing such allergy may be significantly increased.


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