QOL in hypertensive patients is improved when BP is controlled with medication regimes that are well tolerated, usually involving multidrug, low-dose strategies. All drugs may have adverse effects, but low-dose HCTZ appears to be as well tolerated as other medications. QOL drug comparisons with different drugs are fairly equal with low-dose therapy. A multidrug strategy using low dosages in combination is probably the best approach to BP control without interfering with the enjoyment of life. Compliance strategies are challenging and must address multiple issues.
Joel Handler, MD, Kaiser Permanente, 411 Lakeview Avenue, Anaheim, CA 92807.
© 2005 Le Jacq Communications, Inc.
Cite this: Quality of Life and Antihypertensive Drug Therapy - Medscape - May 01, 2005.