A Review of Smoking Cessation Interventions

Ashish Maseeh, MD, and Gagandeep Kwatra, MD

In This Article


Every 8 seconds, a person dies of a tobacco-related disease, and almost as quickly another victim is recruited.[1] Cigarette smoking is a major preventable cause of morbidity and is expected to cause up to 450 million deaths in the next 50 years.[2] While the association of smoking with cardiovascular diseases, cancer, respiratory diseases, and gastric ulceration has been documented extensively,[3] it may also accelerate early menopause through its antiestrogen effect.[4]

Smoking cessation may be defined as validated sustained abstinence from cigarettes and/or other tobacco products for at least 6 months, but preferably for a year.[5] Regardless of age at the time of quitting, cessation decreases the risk of as well as delays the progression of smoking-related diseases while increasing life expectancy.[6] Another important consideration is the cost-effectiveness of smoking cessation support, which is far superior to that of many other potentially life-saving interventions, and there is a distinct economic advantage in encouraging patients to quit.[7]


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