While recent legal and economic incentives have encouraged pharmaceutical companies to obtain more data regarding dosing, efficacy, and side effects of medications used in pediatric preparations, there are still problems obtaining adequate patient sample sizes and objective measurement of symptoms and outcomes for such studies. Pediatric dosage information has become slowly available, but many of the medications commonly used in children still do not have pediatric dosing labeling, presenting a dilemma when treating these patients. Infants and neonates in particular are subject to a much greater risk of systemic side effects. Physicians should consider carefully the risk/benefit profile when prescribing eye drops in children to establish the appropriate dosage while minimizing risk, and monitor patients closely during and after treatment for local and systemic side effects.
David K. Wallace, MD, UNC Dept of Ophthalmology, 5105 Bioinformatics; CB #7040, Chapel Hill, NC 27599-7040. email: email@example.com
Compr Ophthalmol Update. 2005;6(2):85-101. © 2005 Comprehensive Ophthalmology Update, LLC
Cite this: Ophthalmic Medications in Pediatric Patients - Medscape - Mar 01, 2005.