A Review of the Metabolic Effects of Sibutramine

T. D. Filippatos; D. N. Kiortsis; E. N. Liberopoulos; D. P. Mikhailidis; M. S. Elisaf


Curr Med Res Opin. 2005;21(3):457-468. 

In This Article


Relevant articles were identified through a Medline search (up to December 2004) using the terms 'sibutramine, Meridia, Reductil, obesity, weight loss, metabolic parameters, metabolic effects, diabetes, dyslipidaemia, uric acid, fibrinogen, homocysteine, leptin, adiponectin, resistin, adipocytokines, C-reactive protein, polycystic ovary syndrome, metabolic syndrome, atherosclerosis, smoking, endothelium, thrombosis, plasminogen, platelets and non-alcoholic fatty liver disease'. We also conducted a manual search of some of the reference lists from original research papers and review articles. We selected papers with larger numbers of patients and with key messages that related to the topic of this review (i.e. the metabolic effects of sibutramine).


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