Periodontitis and CVD: What Is the Link?

W. Steven Pray; Joshua J. Pray


US Pharmacist. 2005;30(2):16-22. 

In This Article

Does Periodontitis Cause CVD by Altering C-Reactive Protein?

Investigators studied 94 patients who were systemically healthy but who had severe generalized periodontal disease, defined as periodontal probing depths greater than 6 mm and loss of marginal alveolar bone greater than 30%, affecting 50% or more of the dentition.[5] They measured the C-reactive protein (CRP), a sensitive marker of inflammatory status that may be a predictor for future cardiovascular events (e.g., atherogenesis).[1] More severe and widespread periodontitis increased the risk of CRP-associated CVD.


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