Periodontitis and CVD: What Is the Link?

W. Steven Pray; Joshua J. Pray

Disclosures

US Pharmacist. 2005;30(2):16-22. 

In This Article

Which Patients Are at Greatest Risk?

There are two groups of disease risk factors: nonmodifiable or modifiable.[7] Because nonmodifiable risk factors, such as increasing age or genetic makeup, cannot be altered, they will remain potential causes of disease for the life of the patient. However, patients can decrease the likelihood of developing diseases by controlling modifiable risk factors, such as weight, lack of exercise, cholesterol levels, sodium intake, and smoking. Thus, discovering any new modifiable risk factor for a serious disease has profound consequences for people, since they can voluntarily begin to decrease disease risk.

In the case of periodontitis, all patients with the infection are not at equal risk of CVD, since most of those conditions are multifactorial in origin. The risk may be modified by environmental or genetic factors. For instance, smoking or obesity may worsen the prognosis, while a favorable genetic profile might reduce susceptibility.

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