Should We Routinely Measure Renin Levels to Diagnose and Treat Patients With Hypertension? (Part I)

The Argument For

Phyllis August, MD, MPH

In This Article


Measuring renin levels can be helpful in the management of hypertension. Although baseline renin measurements may lead to better BP control and the use of fewer medications, this hypothesis has never been formally tested in a large clinical trial. A clinical trial measuring surrogate end points such as BP control, cost, and time to control BP would provide useful information and should be considered. Renin measurement may also be useful in the management of patients already on treatment in whom BP is not at target. Measurement of renin levels is also a first step in the investigation of secondary hypertension, particularly mineralocorticoid hypertension.

The print version of this article was originally certified for CME credit. For accreditation details, contact the publisher. Lejacq Communications, Inc., Office of Medical Affairs, Lenox Hill Hospital, 100 East 77th Street, New York, NY 10021.