Community Associated Methicillin-Resistant Staphylococcus Aureus: A Review

Michael J. Rybak, PharmD; Kerry L. LaPlante, PharmD


Pharmacotherapy. 2005;25(1):74-85. 

In This Article

Risk Factors

It is of vital importance to identify risk factors for CA-MRSA to enable clinicians to rapidly recognize and appropriately treat infected patients.[23,33] Several studies have demonstrated an increase in the prevalence of CA-MRSA; however, risk factors have not been fully characterized.[3,7,15,19,20,21,23,25,34] Children and young adults have served as the primary patient source for a significant number of these studies.[23,35] Other than injection drug use, no other community-associated risk factors have been identified.[7,36] Unfortunately, great inconsistencies exist in the definitions of CA-MRSA in these investigations. Early studies did not discuss exclusion criteria, whereas other studies discussed exclusion criteria for health care contact ranging from a few months to up to 1 year after MRSA colonization.[15,21,23,34,37] Most report that routine contact with health care facilities was a significant risk factor for CA-MRSA acquisition.


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