Brain Metastasis From Cervical Carcinoma -- A Case Report

Maheshwari Amita, MD; Gupta Sudeep, MD; Wuntkal Rekha; Kulkarni Yogesh; Tongaonkar Hemant, MD

In This Article

Abstract and Introduction

Brain metastases from cervical carcinomas are extremely rare. We report a patient with squamous cell carcinoma of the cervix who developed an isolated left parietooccipital lobe metastasis within 4 months of treatment of the primary disease. The presenting symptoms of the metastatic disease were visual disturbance, headache, and vomiting. The patient was successfully treated by surgical excision of the metastasis and adjuvant whole brain radiation therapy, and she was disease-free at the 6-month follow-up after treatment of the recurrence.

Cervical cancer is the most common malignancy in Indian women, with an annual incidence of approximately 100,000 cases. Cervical cancers usually spread by local extension and through the lymphatics to the retroperitoneal lymph nodes. Metastases to the central nervous system from cervical cancer are extremely rare. They are usually seen late in the course of the disease, and have poor prognosis. Due to the rarity of this event, there are very few reports in the literature regarding the optimal management and prognosis of these patients. We report the case of a woman with squamous cell carcinoma of the cervix, with a left parietooccipital lobe metastasis, who was managed successfully. A summary of the relevant literature is also presented.


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