Melanie B. Peachell, MD; Nestor L. Muller, MD, PhD


Semin Respir Crit Care Med. 2004;25(5) 

In This Article

Microscopic Polyangiitis

Microscopic polyangiitis is a systemic disease characterized by necrotizing vasculitis with few or no immune deposits that involves predominantly or exclusively the arterioles, venules, and capillaries.[1] The most common clinical manifestations are glomerulonephritis, dyspnea, cough, hemoptysis, fever, myalgia, and arthralgia.[43,44]

The radiological manifestations consist of patchy or confluent bilateral areas of consolidation due to diffuse pulmonary hemorrhage. The airspace consolidation tends to involve mainly the lower lung zones.[44]


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