Smallpox: What the Dermatologist Should Know

Generalized Vaccinia

Generalized vaccinia, from hematogenous dissemination of vaccinia virus, displays a widespread macular and papular or vesicular eruption about 6-9 days after primary vaccination.^[50] It occurs in about one in every 5000 vaccinations. Although usually self-limited and not requiring treatment in persons with normal immunity, it may cause severe toxicity in immunocompromised individuals and require VIG treatment.

Skinmed. 2004;3(4) © 2004 Le Jacq Communications, Inc.

Cite this: Smallpox: What the Dermatologist Should Know - Medscape - Jul 01, 2004.