Tissue Microarrays: A Current Medical Research Tool

Iqbal S. Shergill; N. K. Shergill; M. Arya; H. R. H. Patel


Curr Med Res Opin. 2004;20(5) 

In This Article


Currently, the TMA is mainly used for the high throughput investigation of candidate genes, and their proteins, identified by molecular biology techniques such as DNA microarrays. Studies demonstrate their accuracy and reliability compared to standard histological techniques as well as exhibiting correlation with clinico-pathological information to determine progression of disease and prediction of outcome. In the future, it is anticipated that doctors in primary care, and hospital practice will be able to use the outcomes from this method to assist in the diagnosis, prognosis and development of novel therapies for individual patients, particularly in diseases such as cancer.