Inherited Adrenal Hypoplasia: Not Just for Kids!

Lin Lin; John C. Achermann

Disclosures

Clin Endocrinol. 2004;60(5) 

In This Article

Resistance to ACTH Action

ACTH has an important tropic effect on adrenal development via the melanocortin-2 receptor (MC2R, ACTH receptor) and subsequent downstream signalling pathways. Abnormalities in these signalling processes result in adrenal hypoplasia due to ACTH resistance.

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