Stability of Advanced Life Support Drugs in the Field

Mark A. Gill; Alice Z. Kislik; Lana Gore; Angela Chandna

Disclosures

Am J Health Syst Pharm. 2004;61(6) 

In This Article

Results

Atropine, epinephrine, and lidocaine syringes were studied at 14 fire stations throughout Los Angeles County and at a temperature-controlled laboratory during the summer of 1999. There was no evidence of drug degradation at any site, temperature, or time point ( Table 1 ). These drugs were exposed to temperatures as high as 125.6 °F (52 °C) at the desert site ( Table 4 ). On the other hand, the weather was relatively mild for the Greater Los Angeles area, with average temperatures as low as 67 °F (19.4 °C) at a coastal station to a high of 82.8 °F (28.2 °C) at an inland location. Seven sites exceeded the threshold temperature of 104 °F (40 °C) for as little as 30 minutes and as long as 795 minutes, but none approached the 24-hour total time that would a priori suggest that degradation occurred. Ten of the sites achieved an MKT higher than 77 °F (25 °C), and 6 of these 10 sites achieved an MKT higher than 83 °F (28.3 °C), with the highest MKT calculated being 84.1 °F (28.9 °C) over a 45-day period.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.

processing....