Diabetic Mastopathy

J. Andrew Keyoung, MD, Rebecca A. Zuurbier, MD, Theodore N. Tsangaris, MD, Norio Azumi, MD, Erini Makariou, MD

Disclosures

Appl Radiol. 2003;32(9) 

In This Article

Case Summary

A 38-year-old woman with a 22-year history of type 1 insulin-dependent diabetes presented with a complaint of a lump in the left breast. Physical examination revealed a palpable nodule in the left breast at the 2 o'clock periareolar region. Diagnostic mammography was performed (Figure 1). Directed ultrasound was then performed (Figure 2). Based upon these findings, the patient underwent ultrasound-guided core breast biopsy (Figure 3).

(A) Mediolateral and (B) craniocaudal mammograms of the left breast show heterogeneously fibroglandular pattern of breast parenchyma.

(A) Mediolateral and (B) craniocaudal mammograms of the left breast show heterogeneously fibroglandular pattern of breast parenchyma.

(A) Transverse and (B and C) long-axis sonograms of the area of palpable nodule reveal an ill-defined bordered area of dense acoustical shadowing measuring 4 × 2 × 2 cm with hypoechoic fingerlike extensions and some lobulations (arrows) at the posterior margin.

(A) Transverse and (B and C) long-axis sonograms of the area of palpable nodule reveal an ill-defined bordered area of dense acoustical shadowing measuring 4 × 2 × 2 cm with hypoechoic fingerlike extensions and some lobulations (arrows) at the posterior margin.

(A) Transverse and (B and C) long-axis sonograms of the area of palpable nodule reveal an ill-defined bordered area of dense acoustical shadowing measuring 4 × 2 × 2 cm with hypoechoic fingerlike extensions and some lobulations (arrows) at the posterior margin.

Core needle biopsy specimen of the palpable nodule reveals dense stromal fibrosis (arrows) and occasional periductal lymphocytic infiltration (arrowheads) (Hematoxylineosin stain; original magnification, ×40)

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