Chitosan for Weight Loss and Cholesterol Management

Kelly M. Shields, Pharm.D., Nick Smock, Pharm.D., Cydney E. McQueen, Pharm.D., Patrick J. Bryant, Pharm.D., FSCIP


Am J Health Syst Pharm. 2003;60(13) 

In This Article


Oral administration of chitosan has been studied in clinical trials for two of its reported therapeutic uses, weight control and cholesterol management. The myriad of other uses are supported by only limited anecdotal evidence.

Chitosan has a variety of well-accepted uses in pharmaceutical manufacturing: to mask bitter tastes in oral formulations,[4] as an excipient in tablets, as a disintegrant to improve drug dissolution, as a vehicle for parenteral drug-delivery devices, and as a carrier in controlled-release drug systems.[3,5] Chitosan has also been used in water purification plants to absorb toxic substances.[6]


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