Improvement in Hypertrophic Cardiomyopathy After Significant Weight Loss: Case Report

Gabriel I. Uwaifo, MD, Erica M. Fallon, BS, Karim A. Calis, PharMD, MPh, Bart Drinkard, PT, MSPT, CCS, Jennifer R. McDuffie, PhD, Jack A. Yanovski, MD, PhD


South Med J. 2003;96(6) 

In This Article


On the basis of our findings, it seems that in patients with familial hypertrophic cardiomyopathy who are obese, weight loss can have significant beneficial anatomic and physiologic effects that result in improved cardiac contractility, reduction in cardiac hypertrophy, and reduction in myocardial oxygen demand. This benefit could potentially result in significant long-term improvement in cardiac risk in this subgroup of patients. We think that significant, sustained weight loss should be included as one of the multimodal initial management strategies in this subgroup of patients.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as: