Ovarian Cancer and Fertility Medications: A Critical Appraisal

S. Kashyap, M.D., F.R.C.S.(C), O.K. Davis, M.D., F.A.C.O.G.


Semin Reprod Med. 2003;21(1) 

In This Article

Study Question

Do fertility medications cause ovarian cancer? We are interested in a patient population of infertile patients who have undergone ovulation induction for IVF versus infertile patients who have not received ovulation induction for IVF. The following medications are used during ovulation induction: clomiphene citrate, human menopausal gonadotropin, follicle-stimulating hormone, and gonadotropin-releasing hormone analogs. The outcome of interest is primary, new onset ovarian cancer in exposed infertile patients when compared to unexposed infertile controls.


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