Highlights From the Society for Gynecologic Investigation 51st Annual Meeting

John F. Randolph, Jr, MD


April 18, 2003

In This Article

Differentiation of Human Bone Marrow Stem Cells Into Human Endometrium

Hugh Taylor from Yale University, New Haven, Connecticut, then presented his work investigating the potential ability of human bone marrow stem cells to differentiate into human endometrium. Endometrium obtained from women at least 2 years out from a partially matched bone marrow transplant was shown to contain both gland and stromal cells that had to have originated in the donated marrow. He also showed a mouse endometriosis model in which marrow stem cells were present in endometriosis. This suggests that endometriosis could develop in the absence of a uterus and presents a possible explanation for endometriosis in remote sites, such as the nose or pleura.


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