Highlights From the Society for Gynecologic Investigation 51st Annual Meeting

John F. Randolph, Jr, MD

April 18, 2003

Differentiation of Human Bone Marrow Stem Cells Into Human Endometrium

Hugh Taylor from Yale University, New Haven, Connecticut, then presented his work investigating the potential ability of human bone marrow stem cells to differentiate into human endometrium. Endometrium obtained from women at least 2 years out from a partially matched bone marrow transplant was shown to contain both gland and stromal cells that had to have originated in the donated marrow. He also showed a mouse endometriosis model in which marrow stem cells were present in endometriosis. This suggests that endometriosis could develop in the absence of a uterus and presents a possible explanation for endometriosis in remote sites, such as the nose or pleura.

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Cite this: Highlights From the Society for Gynecologic Investigation 51st Annual Meeting - Medscape - Apr 21, 2003.

Introduction
Genetic Regulation of the Very Early Development of Human Ovarian Follicles
Differentiation of Human Bone Marrow Stem Cells Into Human Endometrium
Hypoglycemia in Pregnancy and Reproductive Outcome
Potential Role for Inflammation in the Initiation of Preterm Labor
Progesterone and Estrogen Regulate Each Other Through Receptor Modulation
The Origins of Preeclampsia
Call for the Evolution of Reproductive Research
Fetal Origins of Adult Diseases -- Insulin Resistance

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