Effects of Intravenous Magnesium Sulfate on the QT Interval in Patients Receiving Ibutilide

Michael F. Caron, Pharm.D., Jeffrey Kluger, M.D., James P. Tsikouris, Pharm.D., Arnold Ritvo, M.D., James S. Kalus, Pharm.D., C. Michael White, Pharm.D.


Pharmacotherapy. 2003;23(3) 

In This Article


Our study results suggest that prophylactic administration of intravenous magnesium sulfate prevents increases in the QT and QTc interval 30 minutes after the last infusion of ibutilide in patients with atrial fibrillation or flutter. No other changes in standard electrocardiographic variables, QT or QTc interval dispersion, or heart rate were observed.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.