Nancy L. Stitt, RN, BSN

Disclosures

April 03, 2003

Epidemiology of Posttransplant Infection

Specific etiologies, predisposing factors, frequency, and type of posttransplant infection differ and vary depending on the organ transplanted and the individual transplant center. However, the major factor responsible for posttransplant infection in all transplanted organs is the use of immunosuppression, which alters normal protective responses. A predisposing factor to infection in the transplant recipient is the preoperative condition of the patient (ie, presence of end-stage organ disease [uremia, cirrhosis, cardiomyopathy], nutritional status, splenic function). Nosocomial factors that cause shifts in microbial flora include surgical and/or invasive procedures, the hospital and critical care environments, the presence of multiresistant hospital organisms, administration of antibiotics, and immunosuppression.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....