Menopause, Epilepsy, and AEDs
Women with catamenial seizure patterns may experience improved seizure control after menopause. However, during perimenopause, when cycles become irregular and there are fluctuations in gonadal steroids, seizure patterns may change and seizure frequency may worsen.[21] In addition, postmenopausal estrogen replacement may exacerbate seizures in some women with epilepsy.[22]
Semin Neurol. 2002;22(3) © 2002 Thieme Medical Publishers
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