Ductal Lavage for Breast Cancer Risk Assessment

Lisa A. Newman, MD, MPH, FACS, Cassann Blake, MD

Disclosures

Cancer Control. 2002;9(6) 

In This Article

Conclusions

Ductal lavage is promising as a risk assessment adjunct. It is a minimally invasive procedure that is well-tolerated by patients, and it is an additional mechanism for identifying women who harbor atypical hyperplasia in their breast ductal system. Ductal lavage is therefore a potentially valuable method of estimating individualized risk, and it can identify women who may derive a significant benefit from risk reduction strategies such as chemoprevention. As we develop a better understanding of the molecular changes that occur during breast cancer pathogenesis, we are likely to identify other molecular markers that may be detected in ductal fluid, and these markers may become important in assessing risk as well as in monitoring response to treatment for patients with an established breast cancer diagnosis.

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