Summary and Conclusion
The first decade and a half of the study of SLE-associated cognitive dysfunction focused primarily on its recognition and identification of patterns and risk factors. Despite the variability in study results, it is now generally well accepted that cognitive dysfunction is a clinically important manifestation of SLE with many etiologic factors contributing to its presentation. More recently, we have seen novel approaches to the study of SLE-associated cognitive dysfunction with respect to its etiology, imaging, and course. It is only through continued and unique research approaches that elucidating the nuances of this complex issue will be possible, with the additional goal of establishing effective treatment strategies for SLE patients with neuropsychiatric manifestations of disease.
ACR, American College of Rheumatology; CSF, cerebrospinal fluid; SLE, systemic lupus erythematosus
Correspondence to Melanie J. Harrison, MD, MS, Assistant Professor of Clinical Medicine, Hospital for Special Surgery, Weill Medical College of Cornell University, Division of Rheumatology, 535 East 70th Street, New York, NY 10021 USA; e-mail: firstname.lastname@example.org
Curr Opin Rheumatol. 2002;14(5) © 2002 Lippincott Williams & Wilkins
Cite this: Cognitive Dysfunction in Neuropsychiatric Systemic Lupus Erythematosus - Medscape - Nov 01, 2002.