Molecular Genetics of Head and Neck Cancer

Lyon L. Gleich, MD, Frank N. Salamone, MD

Disclosures

Cancer Control. 2002;9(5) 

In This Article

Conclusions

Abnormalities of many genes critically involved in the regulation of the cell cycle are found in head and neck cancer. Detection of these genetic changes may assist in both the diagnosis and treatment of head and neck cancer in the future. Further research is needed to clarify how tumor genotype correlates with prognosis. In addition, simpler and less costly methods of detection need to be developed.

Although genetic and biologic therapies are still in the early phases of development, they hold promise for the treatment of head and neck cancer by addressing the fundamental defect of the malignant cell.

This article was originally certified for CME credit. For accreditation details, contact the publisher.
H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, Tampa, FL 33612. Telephone: (813) 632-1349. Fax: (813) 903-4950. Email: ccjournal@moffitt.usf.edu. Cancer Control is included in Index Medicus/MEDLINE and EMBASE/Excerpta Medica.)

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