Surgical Management of Bladder Carcinoma

Rafael Carrion, MD, John Seigne, MB

Disclosures

Cancer Control. 2002;9(4) 

In This Article

Results of Radical Cystectomy: Tumor Control

The significant improvements in clinical outcomes over the past 25 years can be attributed to advances in surgical technique and in medical and anesthetic care. Overall recurrence-free and survival rates vary among institutions. However, higher pathological stage and increased lymph node status are generally associated with increased recurrence rates and worse cancer specific survival. Overall, a patient undergoing a radical cystectomy for invasive bladder cancer has an approximate 60% to 70% 5-year disease-free survival rate. Subdivided, this percentage can increase to greater than 70% for organ-confined lymph node-negative bladder tumors and can decrease to 40% to 50% for those patients with non-organ-confined lymph node-positive bladder tumors. In a review of the literature, this latter group consistently demonstrates higher rates for recurrence and worse survival compared to those with organ-confined disease.[28,50,51,52,53,54] Representative results of tumor control from contemporary radical cystectomy series are presented in Table 4 .

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.

processing....