Surgical Management of Bladder Carcinoma

Rafael Carrion, MD, John Seigne, MB


Cancer Control. 2002;9(4) 

In This Article

Results of Radical Cystectomy: Tumor Control

The significant improvements in clinical outcomes over the past 25 years can be attributed to advances in surgical technique and in medical and anesthetic care. Overall recurrence-free and survival rates vary among institutions. However, higher pathological stage and increased lymph node status are generally associated with increased recurrence rates and worse cancer specific survival. Overall, a patient undergoing a radical cystectomy for invasive bladder cancer has an approximate 60% to 70% 5-year disease-free survival rate. Subdivided, this percentage can increase to greater than 70% for organ-confined lymph node-negative bladder tumors and can decrease to 40% to 50% for those patients with non-organ-confined lymph node-positive bladder tumors. In a review of the literature, this latter group consistently demonstrates higher rates for recurrence and worse survival compared to those with organ-confined disease.[28,50,51,52,53,54] Representative results of tumor control from contemporary radical cystectomy series are presented in Table 4 .


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