Product Availability and Preparation
Naloxone is available as Narcan® (Endo Pharmaceuticals) and as a generic product. The 0.4 mg/ml strength is produced in 1 ml amps and 1 ml syringes, as well as 1, 2, and 10 ml vials. The 1 mg/ml concentration is available in 2 ml amps and 10 ml vials. The 0.02 mg/ml strength, referred to as the neonatal injection, is available in 2 ml amps or vials. The use of this lower concentration is no longer recommended, as it can result in delivery of excessive fluid volumes. Naloxone may be diluted with normal saline or 5% dextrose solutions. It should not be mixed with preparations containing bisulfites or drugs with an alkaline pH.
Pediatr Pharm. 2002;8(8) © 2002 Children's Medical Center, University of Virginia
Cite this: Naloxone for the Reversal of Opioid Adverse Effects - Medscape - Aug 01, 2002.